More sedating than
Benadryl, and many other older antihistamines, such as Chlor-Trimeton (chlorphenirimine), are available OTC without a prescription.
Newer, low-sedating antihistamines, such as Claritin and Zyrtec, tend to have fewer anticholinergic side effects.In fact, numerous readers of this site who have used Xyzal reported an increase in appetite and weight gain.The package insert for Xyzal confirms weight gain as a known side effect, but reports this as only occurring in 0.5% of people in studies who were taking this medication.These conditions may include: Antihistamines Available Over-the-Counter (OTC)Probably the most well-known oral antihistamine is Benadryl, which is an older, sedating antihistamine.While Benadryl is a reasonable medication for the treatment of various allergic conditions, side effects limit its routine use, especially during the daytime.Antihistamines and Sedation Older antihistamines, such as Benadryl and Atarax, have a significant amount of anticholinergic side effects.
These side effects may include dry mouth, drowsiness, constipation and urinary retention.
While these newer antihistamines may still cause drowsiness or a dry mouth, they haven’t been shown to impair a person’s ability to operate a motor vehicle.
Allegra is the only antihistamine that is truly considered to be non-sedating.
Histamine binds to the histamine receptor, which is present on various cells in the body, and results in allergic symptoms such as sneezing, itchy eyes, itchy nose, hives, or even anaphylaxis.
Antihistamines are medications that block the receptor for histamine, thereby stopping the symptoms that histamine causes. Antihistamines are commonly used for the treatment of various allergic diseases, and can be taken in oral, nasal spray, eye drop, and injected forms.
Histamine is a chemical that is normally produced in the body and stored in allergic cells, such as mast cells and basophils.